Recent Comments

Here are the last few comments on the blog. Please remember to read the comments and privacy policy for the blog before jumping into a discussion.

  • Comment on When You Need A Win by wzrd1 April 21, 2017 22:38
    Tempting. Took a $3k loan out on my 401k, that should get me a decent vehicle. Havn't tried Flonase, 50mg diphenhydramine seems to be doing the job well enough, once I actually get around to taking them.
  • Comment on When You Need A Win by Rene Najera April 21, 2017 17:05
    Luckily, I have not been as itchy this time around. I did one year, but I don't know what exactly happened. It got so bad I also didn't wear anything that would show the blood. This year it was my nose and eyes... I had water coming out of my nose and dripping everywhere if I couldn't get to it, like when I was carrying the groceries into the house. Gross.
  • Comment on When You Need A Win by Rene Najera April 21, 2017 17:04
    Do we need to get you a hover round? Also, Flonase is superb. It kicks in after two days, but, once it does, it's the best.
  • Comment on When You Need A Win by Chris April 20, 2017 19:52
    The blasted alder trees started to spread their pollen early this year, January instead of February. I did not get the sniffles, I got the itchies. At night. I am finally recovering from my involuntary self-mutilation during sleep that caused scratches all over my arms, legs, back and stomach. Fortunately not much to my face, though I did wake up to find my ears had some scratches. Oh, and I did wake up in the middle of the night and take a Benadryl. It helped, a little. I think I can now go back to swimming. I was afraid of actually bleeding in the pool. I did wear lots of black to cover where I bled. I also figured out a good way to get blood out of clothes and sheets: first do a warm soak with oxygen bleach. Every season is so different. One year my face was so swollen, especially around my eyes, that I could barely see.
  • Comment on When You Need A Win by wzrd1 April 20, 2017 19:10
    Tell me about morning, noon and night sickness! My wife had it bad, each time. To the point where I worried about malnutrition! Amazingly, she and the baby survived her bubble-belly stage of life. When she's felling down a bit, due to the gravity of her gravid condition, spring a reminder on her, "Weebles wobble, but they don't fall down". 😉 My wife was rolling, very nearly literally, after I got her with that one. 😀 As for allergies, yeah. Worse here in Louisiana, less freezing (only a few days total below freezing this winter), making allergy season a living hell. Living off of 50 mg diphenhydramine. It has felt like I was literally drowning from post nasal drip. Getting plenty of exercise here. Car blew a head gasket, so it's heel and toe express wherever I need to go. Well, heel and toe and cane express.
  • Comment on Face It, You Think You Know Better Than Me by Rene Najera April 10, 2017 20:14
    My money's on them surviving World War III instead of us.
  • Comment on Face It, You Think You Know Better Than Me by wzrd1 April 10, 2017 20:05
    BTW, Ren, PZ Meyers was recently railing about some lousy reporting on RNA editing in cephalopods, which prompted me to look into some of the literature. Apparently, "broken" DNA that makes malfunctioning RNA can be edited by repair proteins in cephalopods. A *lot* of such protein editing was found, far more than is present in mammals. I guess that one could say, in some ways, cephalopods are more advanced than we are, at a cellular level. 😉
  • Comment on Face It, You Think You Know Better Than Me by Rene Najera April 10, 2017 05:10
    Here's a good primer on "epigenetics." Hint: It doesn't mean what you think it means. Basically, CT, you're the kind of person this blog post was written about, i.e. someone who thinks they know better when they don't. Article: From that article: "There has been a disturbing fixation on mapping patterns of DNA methylation, on the assumption that finding these tell-tale tags on genes means that they are switched off. But is DNA methylation or histone modification a cause – the actual thing that switches a gene on or off – or is it just a consequence of other underlying processes at work? To draw an analogy, is it like the locked door of a shut-up shop, or just the “closed” sign swinging against the windowpane, a visible readout of a more fundamental process at work? Most research shows that genes are activated by protein molecules called transcription factors, which sit on short stretches of DNA near genes and act as “control switches” to turn them on. Histone modifications may be important for locking in patterns of gene activity once the transcription factors have got them going, but there’s still a lot we don’t really understand about how it all works."
  • Comment on Face It, You Think You Know Better Than Me by Chris April 7, 2017 19:06
    At the bottom of the comments I posted a video on the known autism causing gene sequences. I assume you are not going to bother watching it, because you have come up with your own theory (beets? Not different screening standards?). Anyway, starting at about 35 minutes in there is a pie chart of what is known. I will summarize it for you (there made errors in the transcription because the lack of video resolution, and my typos): 5% are Genetic Syndromes like Fragile X, Tuberous Sclerosis (TSC1 and TSC2), .... etc 10% are Copy Number Variants like 15q11-1, 1q21.... etc. 2% are 16p11.2 30% are De novo gene variants like DYRK1A, ADNP, ... etc 1% CHD8 8% are rare inherited gene mutations (letters too small to make out). And 45% are still unknown, hence the massive recruitment for families for SPARK for Autism by the Simons Foundation (link in my other comment). At around the 57th minute there is a slide of various groups parents have formed around the specific genetic sequence their child has. It includes FamiliesSCN2A and ADNPkids. At 59 minutes there is a slide showing how knowing the specific gene sequence is important. For instance those with SCN1A need to avoid sodium channel blockers, and those with SCN8A need to use sodium channel blockers. Then the presentation concludes on research programs at the Simons Foundation and our local university. Then the presenters took questions.
  • Comment on Face It, You Think You Know Better Than Me by wzrd1 April 7, 2017 03:55
    I have to go with Rene here. You try to say something is epigenetic, but not genetic, which is a contradiction. That strongly suggests that you have no clue in the universe what epigenetics actually is, let alone genetics. Here is a hint, this causes one form of autism, but not all forms and not always. 1q21.1 deletion syndrome. Epigenetic, that ain't, as it's partial to full deletion of part of a chromosome 1. Vaccines don't delete sections of any chromosome. You don't even quite understand environmental, which epigenetics may and only may play a part, as teratogens would also play a part, about which, you remain silent. If you want to not be treated like an idiot, do not make idiotic comments that don't stand up to scrutiny by those who know about the subjects that you prove, via your comments, know nothing about.